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Complex DNA knots detected with a nanopore sensor

Authors :
Rajesh Kumar Sharma
Ishita Agrawal
Liang Dai
Patrick S. Doyle
Slaven Garaj
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2b1a76737001404d80ef253081485b51
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-12358-4