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Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets

Authors :
Masashi Fujita
Mei-Ju May Chen
Doris Rieko Siwak
Shota Sasagawa
Ayako Oosawa-Tatsuguchi
Koji Arihiro
Atsushi Ono
Ryoichi Miura
Kazuhiro Maejima
Hiroshi Aikata
Masaki Ueno
Shinya Hayami
Hiroki Yamaue
Kazuaki Chayama
Ju-Seog Lee
Yiling Lu
Gordon B. Mills
Han Liang
Satoshi S. Nishizuka
Hidewaki Nakagawa
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The molecular heterogeneity of primary liver cancer remains to be characterised. Here, the authors perform multi-omics analysis of 259 primary liver cancer tissues and identify three distinct molecular subtypes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2b8bfa4d2fb8409dadad46cf1b22157e
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-34249-x