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SUPPRESSION OF MICE IMMUNE RESPONSE BY ANTIMACROPHAGE SERUM TREATEMENT AND ITS RECONSTITUATION BY MACROPHAGE TRANSPLANTATION

Authors :
N. Mohagheghpour
LK. Nafici
Source :
Iranian Journal of Public Health, Vol 4, Iss 2, Pp 149-153 (1975)
Publication Year :
1975
Publisher :
Tehran University of Medical Sciences, 1975.

Abstract

The immunosuppressive effect of antimacrophage serum (AMS) on the primary immune response of mice to sheep red blood cells (SRBC) was studied. AMS, given before a small dose of antigen, abrogated the immune response. Transplantation of normal, galss-adherent macrophages enabled AMS-treated animals to respond to SRBC, while administration of lymph node lymphocytes did not reveres AMS - induced immunosuppression significantly.

Details

Language :
English
ISSN :
22516085
Volume :
4
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Iranian Journal of Public Health
Publication Type :
Academic Journal
Accession number :
edsdoj.2c599f5f5e45441cb8c6895131232a9e
Document Type :
article