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Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma
- Source :
- Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
- Publication Year :
- 2020
- Publisher :
- Nature Portfolio, 2020.
-
Abstract
- The epigenetic landscape of esophageal squamous cell carcinoma (ESCC) at genome-wide high resolution is incompletely studied. Here, the authors performed an integrated multi-omics analysis of ESCC and non-tumor tissues to define the genome-wide methylome landscape and epigenetic alterations to uncover oncogenic drivers of ESCC.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2d7895e7d5f748e48174da98ff21c531
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-020-17227-z