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Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer
- Source :
- Communications Medicine, Vol 2, Iss 1, Pp 1-8 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- Li et al. report outcomes from the atezolizumab/isatuximab arm of the phase Ib/II MORPHEUS-CRC trial in patients with metastatic colorectal cancer. In addition, the authors leverage historical control data from the phase III IMblaze370 study to provide more precise treatment effect estimates.
- Subjects :
- Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 2730664X
- Volume :
- 2
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Communications Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2d8a6d7f97440f4b6e89b19aac1153c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s43856-022-00155-y