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Biomarkers of systemic inflammation are associated with disease severity and metabolic syndrome in patients with hidradenitis suppurativaCapsule Summary
- Source :
- JAAD International, Vol 15, Iss , Pp 170-178 (2024)
- Publication Year :
- 2024
- Publisher :
- Elsevier, 2024.
-
Abstract
- Background: Biomarkers associated with disease severity and comorbid metabolic syndrome (MetS) in patients with hidradenitis suppurativa (HS) are lacking. Objective: To identify biomarkers associated with disease severity and comorbid MetS in patients with HS. Methods: Data on hospital outpatients with HS were obtained through clinical examination and interviews. Indicators of systemic inflammation; C-reactive protein (CRP), erythrocyte sedimentation-rate (ESR), neutrophil/lymphocyte-ratio (NLR), platelet/lymphocyte-ratio (PLR), monocyte/lymphocyte-ratio (MLR), platelet/neutrophil-ratio (PNR), pan-immune-inflammation-value (PIV), and systemic-immune-inflammatory-index (SII), were calculated from blood samples. Results: Seven hundred patients were included; of those 444 (63.4%) and 256 (36.6%) were female and male, respectively, with a median age of 38.3 years (IQR = 27.9-51.0). Increasing CRP, ESR, NLR, PIV, and SII (P
Details
- Language :
- English
- ISSN :
- 26663287
- Volume :
- 15
- Issue :
- 170-178
- Database :
- Directory of Open Access Journals
- Journal :
- JAAD International
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2d974a173e304ebf96ab43141235f11d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.jdin.2024.03.002