Efficacy Of High Flow Nasal Cannula Oxygenation In Acute Respiratory Failure Patients And Comparing With Noninvasive Positive Pressure Ventilation

The goal of this study is to assess HFNC oxygenation and compare the efficacy of high-flow nasal cannula (HFNC) to noninvasive ventilation (NIV) on oxygenation in patients with acute hypoxemic respiratory failure. The patients were randomly grouped into two groups, 20 in each group. Group 1: treated by high-flow nasal cannula (HFNC) and group 2: treated by non-invasive ventilation. There was a statistically significant difference regarding PaO2/FiO2 at baseline and at the end (P-value < 0.001) in both groups indicating improvement of oxygenation in both groups. There was a statistically significant difference between the two groups regarding the PaO2 and PaO2/FiO2 ratio (P-value < 0.05) at the end of the trial however the degree of oxygenation improvement was significantly higher with NIV group. The conclusion of our study: the use of high flow nasal cannula is effective in improving oxygenation but NIV was superior to HFNC.