Back to Search
Start Over
Risk of Subsequent Primary Cancers Among Adult-Onset 5-Year Cancer Survivors in South Korea: Retrospective Cohort Study
- Source :
- JMIR Public Health and Surveillance, Vol 10, p e48380 (2024)
- Publication Year :
- 2024
- Publisher :
- JMIR Publications, 2024.
-
Abstract
- BackgroundThe number of cancer survivors who develop subsequent primary cancers (SPCs) is expected to increase. ObjectiveWe evaluated the overall and cancer type–specific risks of SPCs among adult-onset cancer survivors by first primary cancer (FPC) types considering sex and age. MethodsWe conducted a retrospective cohort study using the Health Insurance Review and Assessment database of South Korea including 5-year cancer survivors diagnosed with an FPC in 2009 to 2010 and followed them until December 31, 2019. We measured the SPC incidence per 10,000 person-years and the standardized incidence ratio (SIR) compared with the incidence expected in the general population. ResultsAmong 266,241 survivors (mean age at FPC: 55.7 years; 149,352/266,241, 56.1% women), 7348 SPCs occurred during 1,003,008 person-years of follow-up (median 4.3 years), representing a 26% lower risk of developing SPCs (SIR 0.74, 95% CI 0.72-0.76). Overall, men with 14 of the 20 FPC types had a significantly lower risk of developing any SPCs; women with 7 of the 21 FPC types had a significantly lower risk of developing any SPCs. The risk of developing any SPC type differed by age; the risk was 28% higher in young (
- Subjects :
- Public aspects of medicine
RA1-1270
Subjects
Details
- Language :
- English
- ISSN :
- 23692960
- Volume :
- 10
- Database :
- Directory of Open Access Journals
- Journal :
- JMIR Public Health and Surveillance
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2e99c5b76d7e45318279123117468c96
- Document Type :
- article
- Full Text :
- https://doi.org/10.2196/48380