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Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment

Authors :
Eun Chae Lee
Tae Won Ha
Dong-Hun Lee
Dong-Yong Hong
Sang-Won Park
Ji Young Lee
Man Ryul Lee
Jae Sang Oh
Source :
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8367 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

Stroke is the leading cause of death and neurological disorders worldwide. However, diagnostic techniques and treatments for stroke patients are still limited for certain types of stroke. Intensive research has been conducted so far to find suitable diagnostic techniques and treatments, but so far there has been no success. In recent years, various studies have drawn much attention to the clinical value of utilizing the mechanism of exosomes, low toxicity, biodegradability, and the ability to cross the blood–brain barrier. Recent studies have been reported on the use of biomarkers and protective and recovery effects of exosomes derived from stem cells or various cells in the diagnostic stage after stroke. This review focuses on publications describing changes in diagnostic biomarkers of exosomes following various strokes and processes for various potential applications as therapeutics.

Details

Language :
English
ISSN :
14220067 and 16616596
Volume :
23
Issue :
15
Database :
Directory of Open Access Journals
Journal :
International Journal of Molecular Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.2ff879bef4714062b7e68b1662cb7963
Document Type :
article
Full Text :
https://doi.org/10.3390/ijms23158367