Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era

Authors :: Serena Vita
Emanuela Giombini
Patrizia De Marco
Martina Rueca
Cesare Ernesto Maria Gruber
Alessia Beccacece
Laura Scorzolini
Valentina Mazzotta
Carmen Pinnetti
Priscilla Caputi
Daniele Focosi
Enrico Girardi
Andrea Antinori
Fabrizio Maggi
Alessandra D'Abramo
Emanuele Nicastri
Investigation Team Spallanzani COVID-19 case
Source :: Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Publication Year :: 2024
Publisher :: PAGEPress Publications, 2024.
Abstract: Abstract: Im We describe here a single-center case series of 27 IC COVID-19 inpatients (mostly with haematological disorders) treated with a combined therapy based on tixagevimab/cilgavimab (T/C) plus small-molecule antivirals (AV), between April 1 2022 and November 30 2022. Keywords: immunocompromised; SARS-CoV-2 infection; monoclonal antibodies; antivirals; persistent infection; viral evolution

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