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Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’

Authors :
Imran Ghani
Sabina Patel
Prajwal Ghimire
Istvan Bodi
Ranjeev Bhangoo
Francesco Vergani
Keyoumars Ashkan
Jose Pedro Lavrador
Source :
Frontiers in Surgery, Vol 9 (2023)
Publication Year :
2023
Publisher :
Frontiers Media S.A., 2023.

Abstract

Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenual area. Therefore, target subtotal resections using minimal invasive approaches focused in the higher metabolic areas are valuable options to preserve quality of life while addressing specific problems caused by the tumor, such as hydrocephalus or progressive growth of a specific component of the tumor. In this report, the authors explore the potential role of 5-ALA in the identification of highly metabolic areas during SEGA resection in the context of minimal invasive approaches.

Details

Language :
English
ISSN :
2296875X
Volume :
9
Database :
Directory of Open Access Journals
Journal :
Frontiers in Surgery
Publication Type :
Academic Journal
Accession number :
edsdoj.30b4abce73a847bca3979c1b29fdb0c2
Document Type :
article
Full Text :
https://doi.org/10.3389/fsurg.2022.1065979