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Can animal models of disease reliably inform human studies?

Authors :
H Bart van der Worp
David W Howells
Emily S Sena
Michelle J Porritt
Sarah Rewell
Victoria O'Collins
Malcolm R Macleod
Source :
PLoS Medicine, Vol 7, Iss 3, p e1000245 (2010)
Publication Year :
2010
Publisher :
Public Library of Science (PLoS), 2010.

Abstract

H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.

Subjects

Subjects :
Medicine

Details

Language :
English
ISSN :
15491277 and 15491676
Volume :
7
Issue :
3
Database :
Directory of Open Access Journals
Journal :
PLoS Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.30db6f0e822d428383098e05471007b2
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pmed.1000245