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Clinico-pathological factors predicting pathological response in early triple-negative breast cancer

Authors :
Clara Helal
Lounes Djerroudi
Toulsie Ramtohul
Enora Laas
Anne Vincent-Salomon
Maxime Jin
Romain-David Seban
Ivan Bieche
Diana Bello-Roufai
Francois-Clement Bidard
Paul Cottu
Delphine Loirat
Matthieu Carton
Florence Lerebours
Nicolas Kiavue
Emanuela Romano
Claire Bonneau
Luc Cabel
Source :
npj Breast Cancer, Vol 11, Iss 1, Pp 1-9 (2025)
Publication Year :
2025
Publisher :
Nature Portfolio, 2025.

Abstract

Abstract Pathological complete response (pCR) after neoadjuvant chemoimmunotherapy (NACi) is associated with improved patient outcomes in early triple-negative breast cancer (TNBC). This study aimed to identify factors associated with pCR after NACi. This cohort included all patients with stage II-III TNBC treated with NACi who underwent surgery at Institut Curie hospitals between 08/2021-06/2023. Among 208 patients, the overall pCR rate was 70% and was similar in ER

Details

Language :
English
ISSN :
23744677
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
npj Breast Cancer
Publication Type :
Academic Journal
Accession number :
edsdoj.3118c6fb0d44e7188f9835f59a49511
Document Type :
article
Full Text :
https://doi.org/10.1038/s41523-025-00729-8