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Extracorporeal support for patients with acute respiratory distress syndrome
- Source :
- European Respiratory Review, Vol 23, Iss 133, Pp 379-389 (2014)
- Publication Year :
- 2014
- Publisher :
- European Respiratory Society, 2014.
-
Abstract
- Extracorporeal membrane oxygen (ECMO) has been used for many years in patients with life-threatening hypoxaemia and/or hypercarbia. While early trials demonstrated that it was associated with poor outcomes and extensive haemorrhage, the technique has evolved. It now encompasses new technologies and understanding that the lung protective mechanical ventilation it can facilitate is inextricably linked to improving outcomes for patients. The positive results from the CESAR (Conventional ventilation or ECMO for Severe Adult Respiratory failure) study and excellent outcomes in patients who suffered severe influenza A (H1N1/09) infection have established ECMO in the care of patients with severe acute respiratory distress syndrome. Controversy remains as to at what point in the clinical pathway ECMO should be employed; as a rescue therapy or more pro-actively to enable and ensure high-quality lung protective mechanical ventilation. The primary aims of this article are to discuss: 1) the types of extracorporeal support available; 2) the rationale for its use; 3) the relationship with lung protective ventilation; and 4) the current evidence for its use.
- Subjects :
- Diseases of the respiratory system
RC705-779
Subjects
Details
- Language :
- English
- ISSN :
- 09059180 and 16000617
- Volume :
- 23
- Issue :
- 133
- Database :
- Directory of Open Access Journals
- Journal :
- European Respiratory Review
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.31fcaa74a4d465497d1200901870bd1
- Document Type :
- article
- Full Text :
- https://doi.org/10.1183/09059180.00005514