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Trans-illumination intestine projection imaging of intestinal motility in mice

Authors :
Depeng Wang
Huijuan Zhang
Tri Vu
Ye Zhan
Akash Malhotra
Pei Wang
Upendra Chitgupi
Aliza Rai
Sizhe Zhang
Lidai Wang
Jan D. Huizinga
Jonathan F. Lovell
Jun Xia
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Current preclinical imaging of intestine in animal models cannot reveal intestinal dynamics in awake condition. Here the authors report a Transillumination Intestine Projection (TIP) imaging system for free-moving mice, and showed the intestine dynamics in conscious animal in natural physiological states.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3243485b209b4a0f852bd911b08970a2
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-21930-w