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Cervical neoplastic lesions in relation to CD4 T‐lymphocyte counts and antiretroviral therapy among women with clinical stage 1 HIV in Yunnan, China

Authors :
Dong‐Yu Zhang
Wen Chen
Hong‐Yun Zhang
Song‐Qin Lv
Xiao‐Ning Lu
Yan‐Ping Tao
Mi Zhang
Jia‐Fa Liu
Min Yang
You‐Lin Qiao
Dejana Braithwaite
Source :
Kaohsiung Journal of Medical Sciences, Vol 36, Iss 6, Pp 450-459 (2020)
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

Abstract China lacks data demonstrating associations of cervical neoplastic lesions with CD4 T‐lymphocyte (CD4 cell) counts and antiretroviral therapy (ART) among HIV‐infected women, suggesting relevant investigations are needed. A total of 545 HIV‐infected women were enrolled in Yunnan, China, between 2011 and 2013. CD4 cell counts and ART were measured via medical records and cervical neoplastic lesions were measured by professional pathologists. Multivariable logistic models, which treated cervical intraepithelial neoplasia (CIN) 1+ and CIN2+ as outcomes, calculated adjusted odds ratio (aOR) of CD4 cell counts and ART. Subgroup analysis treating CIN1+ as the outcome was conducted by HIV infection duration (

Details

Language :
English
ISSN :
24108650 and 1607551X
Volume :
36
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Kaohsiung Journal of Medical Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.3432e8b7fb30474eb8400a2510e363c0
Document Type :
article
Full Text :
https://doi.org/10.1002/kjm2.12175