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Melanopsin (Opn4) is an oncogene in cutaneous melanoma

Authors :
Leonardo Vinícius Monteiro de Assis
José Thalles Lacerda
Maria Nathália Moraes
Omar Alberto Domínguez-Amorocho
Gabriela Sarti Kinker
Davi Mendes
Matheus Molina Silva
Carlos Frederico Martins Menck
Niels Olsen Saraiva Câmara
Ana Maria de Lauro Castrucci
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Melanopsin (Opn4) is identified as an oncogene in cutaneous melanoma, with the loss of Opn4 found to be associated with reduced proliferation and tumor growth, due to changes in immune responses and Mitf signaling in vitro and in vivo.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.34ff8296efc64f529ce55ec839ae4b5e
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03425-6