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IL-27 Negatively Regulates Tip-DC Development during Infection

Authors :
Gongguan Liu
Osama Abas
Yong Fu
Yanli Chen
Ashley B. Strickland
Donglei Sun
Meiqing Shi
Source :
mBio, Vol 12, Iss 1 (2021)
Publication Year :
2021
Publisher :
American Society for Microbiology, 2021.

Abstract

TNF/iNOS-producing dendritic cells (Tip-DCs) are at the front line as immune effector cells to fight off a broad range of invading microbes. Excessive development of Tip-DCs contributes to tissue destruction.

Subjects

Subjects :
Microbiology
QR1-502

Details

Language :
English
ISSN :
21612129 and 21507511
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
mBio
Publication Type :
Academic Journal
Accession number :
edsdoj.3567fc2977c4bc7affcd6829ff830d0
Document Type :
article
Full Text :
https://doi.org/10.1128/mBio.03385-20