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Association and its population heterogeneities between low-density lipoprotein cholesterol and all-cause and cardiovascular mortality: A population-based cohort study
- Source :
- Chinese Medical Journal, Vol 137, Iss 17, Pp 2075-2083 (2024)
- Publication Year :
- 2024
- Publisher :
- Wolters Kluwer, 2024.
-
Abstract
- Abstract. Background:. The association and its population heterogeneities between low-density lipoprotein cholesterol (LDL-C) and all-cause and cardiovascular mortality remain unknown. We aimed to examine the dose-dependent associations of LDL-C levels with specific types of cardiovascular disease (CVD) mortality and heterogeneities in the associations among different population subgroups. Methods:. A total of 2,968,462 participants aged 35–75 years from China Health Evaluation And risk Reduction through nationwide Teamwork (ChinaHEART) (2014–2019) were included. Cox proportional hazard models and Fine–Gray subdistribution hazard models were used to estimate associations between LDL-C categories (
- Subjects :
- Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 03666999, 25425641, and 00000000
- Volume :
- 137
- Issue :
- 17
- Database :
- Directory of Open Access Journals
- Journal :
- Chinese Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.356c89f0fa714af6854e15ae22d19aaf
- Document Type :
- article
- Full Text :
- https://doi.org/10.1097/CM9.0000000000003199