Phytochemical constituents from the seeds of Calycotome villosa subsp. intermedia

A new dihydroisoquinoline-N-oxide alkaloid 1 together with the previously known methyl 4-hydroxybenzoate 2 were isolated for the first time from the seeds of Calycotome villosa subsp. intermedia. Their structures were elucidated by extensive spectroscopic analysis and in the case of the new alkaloid 1-hydroxymethyl-6,7-dimethoxy-3,4-dihydroisoquinoline-N-oxide 1 by X-ray diffraction analysis.