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Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- Here, the authors perform large-scale high-resolution Parkinson’s disease metagenomics analyses, revealing widespread dysbiosis characterized by overabundance of pathogens, immunogens, toxicants, and curli, reduction in neuroprotective and antiinflammatory molecules, and dysregulated neuroactive signaling.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.36926e90f9f04cf1aa145085ad06354e
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-34667-x