Back to Search
Start Over
Dissociation kinetics of small-molecule inhibitors in Escherichia coli is coupled to physiological state of cells
- Source :
- Communications Biology, Vol 6, Iss 1, Pp 1-7 (2023)
- Publication Year :
- 2023
- Publisher :
- Nature Portfolio, 2023.
-
Abstract
- This study investigates how binding/unbinding kinetics of a benzimidazole-derivative DNA inhibitor in E. coli cells depends on cell growth and physiology and demonstrates the effect of this coupling on drug efficacy.
- Subjects :
- Biology (General)
QH301-705.5
Subjects
Details
- Language :
- English
- ISSN :
- 23993642
- Volume :
- 6
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Communications Biology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.36c37c98fdca416f9549d704ee7452e1
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s42003-023-04604-9