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Specificities of Approaches to Anticoagulant Therapy in Comorbid Patients with Atrial Fibrillation, Diabetes Mellitus and Impaired Kidney Function

Authors :
N. V. Drobotya
E. Sh. Guseynova
A. A. Pirozhenko
Source :
Рациональная фармакотерапия в кардиологии, Vol 16, Iss 2, Pp 296-300 (2020)
Publication Year :
2020
Publisher :
Столичная издательская компания, 2020.

Abstract

Comorbid patients with atrial fibrillation, diabetes mellitus and chronic kidney disease are at high risk of stroke. The direct oral anticoagulants are indicated for them. The choice of a drug should be based on the results of randomized clinical trials, in which the patients profile corresponds to that in the real Russian clinical practice as much as possible. Taking into account the peculiarities of comorbidity in this category of patients, the requirements for their protection should be considered comprehensively. Along with the prevention of thromboembolic complications, it is necessary that the selected direct oral anticoagulant provides a reduction in the risk of cardiovascular complications, which are typical of diabetes mellitus, and slows down the progression of renal filtration function decline. Rivaroxaban may meet these requirements; its use has significant advantage in high adherence to therapy.

Details

Language :
English, Russian
ISSN :
18196446 and 22253653
Volume :
16
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Рациональная фармакотерапия в кардиологии
Publication Type :
Academic Journal
Accession number :
edsdoj.36d2a707fe941bebf87da5711f41c6c
Document Type :
article
Full Text :
https://doi.org/10.20996/1819-6446-2020-04-06