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Synthesis of Triptorelin Lactate Catalyzed by Lipase in Organic Media
- Source :
- International Journal of Molecular Sciences, Vol 13, Iss 8, Pp 9971-9979 (2012)
- Publication Year :
- 2012
- Publisher :
- MDPI AG, 2012.
-
Abstract
- Triptorelin lactate was successfully synthesized by porcine pancreatic lipase (PPL) in organic solvents. The effects of acyl donor, substrate ratio, organic solvent, temperature, and water activity were investigated. Under the optimum conditions, a yield of 30% for its ester could be achieved in the reaction for about 48 h.
Details
- Language :
- English
- ISSN :
- 14220067
- Volume :
- 13
- Issue :
- 8
- Database :
- Directory of Open Access Journals
- Journal :
- International Journal of Molecular Sciences
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.381d85a6912443e9d85dfb2a751c177
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/ijms13089971