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Circ_0000064 promotes high glucose-induced renal tubular epithelial cells injury to facilitate diabetic nephropathy progression through miR-532-3p/ROCK1 axis

Authors :
Huanlan Wang
Shenghua Huang
Taotao Hu
Shizhi Fei
Huanqiao Zhang
Source :
BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-14 (2022)
Publication Year :
2022
Publisher :
BMC, 2022.

Abstract

Highlights 1. Circ_0000064 knockdown relieves HG-induced HK-2 cells injury. 2. Circ_0000064 acts as a sponge of miR-532-3p. 3. MiR-532-3p directly targets ROCK1.

Details

Language :
English
ISSN :
14726823
Volume :
22
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Endocrine Disorders
Publication Type :
Academic Journal
Accession number :
edsdoj.3910ac8276db42418590ed287cd141d4
Document Type :
article
Full Text :
https://doi.org/10.1186/s12902-022-00968-x