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Prevent effect of Bevacizumab and Triamcinolone acetonide on corneal neovascularization induced by penetrating keratoplasty
- Source :
- Guoji Yanke Zazhi, Vol 14, Iss 11, Pp 2016-2018 (2014)
- Publication Year :
- 2014
- Publisher :
- Press of International Journal of Ophthalmology (IJO PRESS), 2014.
-
Abstract
- AIM: To observe the clinical effect subconjunctival bevacizumab and triamcinolone acetonide(TA)on corneal neovascularization(CNV)induced by penetrating keratoplasty.METHODS: Nineteen patients(20 eyes)with CNV induced by penetrating keratoplasty after 3mo were selected and were divided into 4 groups randomly: Group A was control group, group B was treated by subconjunctival of bevacizumab(2.5mg, 0.1mL), group C was treated by subconjunctival of bevacizumab(2.5mg, 0.1mL)and TA(4mg, 0.1mL), group D was treated by subconjunctival of TA(4mg, 0.1mL), one time each month, twice.RESULTS: The average follow-up period was 3a. Visual acuity of groups B and C kept stable or increase slightly. CNV and immunologic rejection were lighten(PCONCLUSION: Treatment of subconjunctival bevacizumab and TA can effectively inhibite CNV and immunologic rejection, also has the therapeutical effect to maintain implant transparence after penetrating keratoplasty.
Details
- Language :
- English
- ISSN :
- 16725123
- Volume :
- 14
- Issue :
- 11
- Database :
- Directory of Open Access Journals
- Journal :
- Guoji Yanke Zazhi
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.39eeb772bf74118b018cf575f9fba65
- Document Type :
- article
- Full Text :
- https://doi.org/10.3980/j.issn.1672-5123.2014.11.27