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Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case–control study

Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case–control study

Authors :
José Antonio Mata-Marín
Moisés Hermilo Martínez-Osio
Carla I. Arroyo-Anduiza
María de los Ángeles Berrospe-Silva
Alberto Chaparro-Sánchez
Itzel Cruz-Grajales
Javier Enrique Cruz-Herrera
Luis Antonio Uribe-Noguez
Jesus E. Gaytán-Martínez
Medardo Jerónimo-Morales
Source :
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Publication Year :
2019
Publisher :
BMC, 2019.

Abstract

Abstract Objective This study was to determine and compare the prevalences of polypharmacy and comorbidities in patients aged 50 years or older with those patients younger than 50 years in a Mexican population. Results One hundred and twenty-five patients were enrolled, 60 (48%) were aged 50 years or older. The median CD4+ cell counts were 509 cells/μL (interquartile range [IQR]: 324–730) for the older patients and 384 cells/μL (IQR: 262–562) (P = 0.021) for the younger patients. Viral suppression were significantly higher in the older group: 80% vs. 63% (P = 0.037). The number of comorbidities was significantly higher in the older group, with a median of 2 (IQR: 2–3) vs. 1 (IQR: 0–1) (P ≤ 0.001). After adjustment of the logistic regression model in the older group, the following comorbidities differed between the age groups: systemic arterial hypertension (odds ratio [OR]: 15.75; 95% confidence interval [CI] 3.49–71.05; P =

Details

Language :
English
ISSN :
17560500
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Research Notes
Publication Type :
Academic Journal
Accession number :
edsdoj.3a84bc1e9e3e4735949a9157683dbc96
Document Type :
article
Full Text :
https://doi.org/10.1186/s13104-019-4576-6