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Skin parasite landscape determines host infectiousness in visceral leishmaniasis

Authors :
Johannes S. P. Doehl
Zoe Bright
Shoumit Dey
Helen Davies
John Magson
Najmeeyah Brown
Audrey Romano
Jane E. Dalton
Ana I. Pinto
Jon W. Pitchford
Paul M. Kaye
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Parasitemia has been considered the main determinant of visceral leishmaniasis transmission. By combining imaging, qPCR and experimental xenodiagnoses with mathematical models, Doehl et al. argue that the patchy landscape of parasites in the skin is necessary to explain infectiousness.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723 and 98016881
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3a887a193dae46a98016881baf0ef70e
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-00103-8