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Activated CD4 T cells/Tregs derived immune-metabolism signature provide precise prognosis assessment for gastric cancer and beneficial for treatment option
- Source :
- Heliyon, Vol 10, Iss 3, Pp e25463- (2024)
- Publication Year :
- 2024
- Publisher :
- Elsevier, 2024.
-
Abstract
- Background: The prognostic significance of the ratio of activated CD4 T cells to Tregs infiltrating tumor tissues in gastric cancer (GC) remains unknown. Materials and methods: For the quantification of infiltration of immune cells, the ssGSEA algorithm, which is a single sample gene set enrichment analysis, was utilized. Group A was defined as having activated CD4 T cells/Tregs >1, while group B was defined as having activated CD4 T cells/Tregs
- Subjects :
- Science (General)
Q1-390
Social sciences (General)
H1-99
Subjects
Details
- Language :
- English
- ISSN :
- 24058440
- Volume :
- 10
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Heliyon
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3a9accfed104684990603e0c1032e74
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.heliyon.2024.e25463