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Correlation of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) with radiographic features of congestion in chest CT scan of patients with COVID-19

Correlation of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) with radiographic features of congestion in chest CT scan of patients with COVID-19

Authors :
Naghmeh Ziaie
Seyed Mohammad Reza Tabatabaie
Khadijeh Ezoji
Ali Bijani
Simin Mouodi
Source :
The Egyptian Heart Journal, Vol 75, Iss 1, Pp 1-6 (2023)
Publication Year :
2023
Publisher :
SpringerOpen, 2023.

Abstract

Abstract Background Given the importance of chest computed tomography (CT) to differentiate congestion from COVID-19 pneumonia, and considering the association of chest CT findings with cardiac biomarkers in patients with concomitant COVID-19 and heart failure, this study was conducted to identify the correlation between plasma NT-proBNP level and radiographic features of congestion in patients with COVID-19. This retrospective cohort research was carried out on adult hospitalized patients with COVID-19 and the plasma concentration of NT-proBNP was measured. The most important findings in chest CT have been considered to differentiate COVID-19 pneumonia from congestion. The study population was divided into two groups based on the presence of these imaging characteristics. Results Totally, 180 patients with a mean age of 59.6 ± 14.6 years were included in the research. The radiographic findings related to congestion have been found in chest CT of 107 (59.4%) patients. Mean plasma concentration of NT-proBNP in patients with and without radiographic features of congestion was 9886.5 ± 12,676 and 2079.9 ± 4209.3 pg/mL, respectively (p

Details

Language :
English
ISSN :
2090911X
Volume :
75
Issue :
1
Database :
Directory of Open Access Journals
Journal :
The Egyptian Heart Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.3bdc25bb8e3d4707960b60084f5f4f45
Document Type :
article
Full Text :
https://doi.org/10.1186/s43044-023-00390-1