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Sperm acrosin activity may be a useful factor in choosing between ICSI and IVF for infertile male patients
- Source :
- Asian Journal of Andrology, Vol 26, Iss 1, Pp 85-90 (2024)
- Publication Year :
- 2024
- Publisher :
- Wolters Kluwer Medknow Publications, 2024.
-
Abstract
- The clinical applications of acrosin activity are limited. We analyzed 61 578 male partners in infertile couples who visited the outpatient department of the Reproductive and Genetic Hospital of CITIC-Xiangya (Changsha, China) between August 2014 and December 2019 to determine the reference ranges and thresholds for acrosin activity in infertile Chinese men; to determine whether correlations exist between acrosin activity and age, sperm concentration, sperm morphology, or sperm motility; and to evaluate whether acrosin activity could serve as an effective prognostic indicator for choosing between in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in the clinic. The cut-off value for the normal reference range of acrosin activity for male partners in infertile couples was 24.78 μIU per 10[6] sperm. There was no significant association between acrosin activity and age, sperm concentration, semen volume, total sperm count, progressive motility, or total motile spermatozoa. A weak positive correlation was found between acrosin activity and normal sperm morphology. There was a statistically significant difference in abnormal acrosome morphology between the group with high acrosin activity (>24.78 μIU per 10[6] sperm) and the group with low acrosin activity (
Details
- Language :
- English
- ISSN :
- 1008682X and 17457262
- Volume :
- 26
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Asian Journal of Andrology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3bee76c88c2a4efa9ab0a1174a946b4a
- Document Type :
- article
- Full Text :
- https://doi.org/10.4103/aja202337