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The upper-airway microbiota and loss of asthma control among asthmatic children

Authors :
Yanjiao Zhou
Daniel Jackson
Leonard B. Bacharier
David Mauger
Homer Boushey
Mario Castro
Juliana Durack
Yvonne Huang
Robert F. Lemanske
Gregory A. Storch
George M. Weinstock
Kristine Wylie
Ronina Covar
Anne M. Fitzpatrick
Wanda Phipatanakul
Rachel G. Robison
Avraham Beigelman
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

How the airway microbiome influences asthma pathophysiology remains unclear. Here, the authors analyse nasal samples of cohort of school-age children with persistent asthma and find that the microbiota’s patterns and composition at time of early loss of asthma control associate with severe asthma exacerbations.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.3c7d234b3d824ae79d9cd5e744d0de74
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-13698-x