TRANSPLANTED HEART. RIGHT VENTRICULAR FAILURE, REJECTION OR MYOCARDITIS?

Authors :: E. N. Ostroumov
E. D. Kotina
R. Sh. Saitgareev
D. V. Shumakov
E. N. Kazakov
V. N. Poptsov
T. M. Polotskaya
A. Y. Kormer
V. M. Zakharevich
I. M. Ilinsky
N. P. Mojeiko
E. I. Ryaboshtanova
L. V. Beletskaya
A. G. Kupriyanova
R. Y. Voilokova
T. V. Pestretsova
S. V. Mironov
A. E. Ermolenko
Source :: Vestnik Transplantologii i Iskusstvennyh Organov, Vol 13, Iss 1, Pp 65-71 (2011)
Publication Year :: 2011
Publisher :: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov, 2011.
Abstract: The differentiation of the cases of the right ventricular failure in transplanted heart should be complex and challenging. The 28-year old man with dilated cardiomyopathy underwent orthotopic heart transplantation. After transplantation developed right ventricular failure. The biopsy (n = 5) didn’t reveal any signs of myocardial rejection. There were noted some signs of inflammation in lateral right ventricular wall only by gated SPECT. The right ventricular failure increased and 6 months later there was successfully performed the heart retransplantation on the patient. The virusological study revealed the Epstein–Barr virus in myocardium. The explanted heart research excluded limphoproliferative disease by immunogystochemical tests. The final diagnosis is myocarditis.