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Case report: Immunotherapy inducing unexpected overall survival in choroidal melanoma: about a case

Authors :
Youssef Elhaitmy
Soukaina El Anssari
Pierre Fournel
Nawfel Mellas
Wafa Bouleftour
Michele Lamuraglia
Source :
Frontiers in Oncology, Vol 14 (2024)
Publication Year :
2024
Publisher :
Frontiers Media S.A., 2024.

Abstract

Choroidal melanoma (CM) is the most common malignant ocular tumor in adults. The current treatment of metastatic CM is limited by the intrinsic resistance of CM to conventional systemic therapies. Immunotherapy alone or in association with cytotoxic treatment became a realist option treatment. Advancements in molecular biology have resulted in the identification of a number of promising prognostic and therapeutic targets. Herein, we report a rare case of 36-year-old patient with metastatic CM who presented a good long response to treatment with double immunotherapy reaching 3 years of overall survival, which has never been described in the literature.

Details

Language :
English
ISSN :
2234943X
Volume :
14
Database :
Directory of Open Access Journals
Journal :
Frontiers in Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.3d4b6b1f0964b67bc10da6129c20af2
Document Type :
article
Full Text :
https://doi.org/10.3389/fonc.2024.1319792