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Central Sensitization in Neurological, Psychiatric, and Pain Disorders: A Multicenter Case-Controlled Study
- Source :
- Pain Research and Management, Vol 2021 (2021)
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background. The role of central sensitization in refractory pain-related diseases has not yet been clarified. Methods. We performed a multicenter case-controlled study including 551 patients with various neurological, psychological, and pain disorders and 5,188 healthy controls to investigate the impact of central sensitization in these patients. Symptoms related to central sensitization syndrome (CSS) were assessed by the Central Sensitization Inventory (CSI) parts A and B. Patients were categorized into 5 groups based on CSI-A scores from subclinical to extreme. The Brief Pain Inventory (BPI), addressing pain severity and pain interference with daily activities, and the Patient Health Questionnaire (PHQ)-9, assessing depressive symptoms, were also administered. Results. CSI-A scores and CSI-B disease numbers were significantly greater in patients than in controls (p
- Subjects :
- Medicine (General)
R5-920
Subjects
Details
- Language :
- English
- ISSN :
- 12036765 and 19181523
- Volume :
- 2021
- Database :
- Directory of Open Access Journals
- Journal :
- Pain Research and Management
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3daa57300f3845d9b81f097c8a531d7d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1155/2021/6656917