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Liver Injury and Elevated Levels of Interleukins, Interleukin-2 Receptor, and Interleukin-6 Predict the Severity in Patients With COVID-19
- Source :
- Frontiers in Public Health, Vol 9 (2021)
- Publication Year :
- 2021
- Publisher :
- Frontiers Media S.A., 2021.
-
Abstract
- The novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide, and the WHO declared it a pandemic on March 11, 2020. Clinical characteristics and epidemiology features of patients infected with SARS-CoV-2 have been explored in the previous study. However, little is known about the combinative association of liver dysfunction and abnormal interleukins (ILs) in severe patients with COVID-19. This study was designed to estimate whether liver dysfunction and abnormal ILs could predict the severity of COVID-19. This study integrated liver function data and ILs data in patients with COVID-19 and found that liver injury and two ILs, interleukin-2 receptor (IL-2R) and interleukin-6 (IL-6), were closely related to the prognosis of patients with COVID-19. This study may give more exact information to clinicians about the prognosis of patients with COVID-19. In addition, this correlational study between liver disorder and ILs may provide a new vision to diagnosis and treatment in patients.
- Subjects :
- COVID-19
IL-2R
IL-6
liver injury
prognosis
Public aspects of medicine
RA1-1270
Subjects
Details
- Language :
- English
- ISSN :
- 22962565
- Volume :
- 9
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Public Health
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3edcbccfb7cd4f82a8c1c9380ffa8a25
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fpubh.2021.778340