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Increased age-associated mortality risk in HLA-mismatched hematopoietic stem cell transplantation

Authors :
Daniel Fürst
Dietger Niederwieser
Donald Bunjes
Eva M. Wagner
Martin Gramatzki
Gerald Wulf
Carlheinz R. Müller
Christine Neuchel
Chrysanthi Tsamadou
Hubert Schrezenmeier
Joannis Mytilineos
Source :
Haematologica, Vol 102, Iss 4 (2017)
Publication Year :
2017
Publisher :
Ferrata Storti Foundation, 2017.

Abstract

We investigated a possible interaction between age-associated risk and HLA-mismatch associated risk on prognosis in different age categories of recipients of unrelated hematopoietic stem cell transplants (HSCT) (n=3019). Patients over 55 years of age transplanted with 8/10 donors showed a mortality risk of 2.27 (CI 1.70–3.03, P

Details

Language :
English
ISSN :
03906078 and 15928721
Volume :
102
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Haematologica
Publication Type :
Academic Journal
Accession number :
edsdoj.3f07344c80a54a35aa1409a024a32b28
Document Type :
article
Full Text :
https://doi.org/10.3324/haematol.2016.151340