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An anticoagulant supercapacitor for implantable applications
- Source :
- Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
- Publication Year :
- 2024
- Publisher :
- Nature Portfolio, 2024.
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Abstract
- Abstract With the rapid advancement of implantable electronic medical devices, implantable supercapacitors have emerged as popular energy storage devices. However, supercapacitors inevitably come into direct contact with blood when implanted, potentially causing adverse clinical reactions such as coagulation and thrombosis, impairing the performance of implanted energy storage devices, and posing a serious threat to human health. Therefore, this work aims to design an anticoagulant supercapacitor by heparin doped poly(3, 4-ethylenedioxythiophene) (PEDOT) for possible applications in implantable bioelectronics. Heparin (Hep), the as-known anticoagulant macromolecule acts as the counterion for PEDOT doping to enhance its conductivity, and the bioelectrode material PEDOT: Hep with anticoagulant activity is synthesized via chemical oxidation polymerization. Concurrently, the anticoagulant supercapacitor is constructed through in-situ polymerization, where PEDOT: Hep and bacterial cellulose as electrode material and electrolyte layer, respectively. Owing to the incorporation of heparin, the supercapacitor exhibits high hemocompatibility with hemolysis rate
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 15
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.40662c1c60442299ac7168224f38547
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-024-54862-2