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An anticoagulant supercapacitor for implantable applications

Authors :
Xiangya Wang
Meimei Yu
Mohammed Kamal Hadi
Jianzhou Niu
Yuxia Zhang
Qi Zhou
Fen Ran
Source :
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Publication Year :
2024
Publisher :
Nature Portfolio, 2024.

Abstract

Abstract With the rapid advancement of implantable electronic medical devices, implantable supercapacitors have emerged as popular energy storage devices. However, supercapacitors inevitably come into direct contact with blood when implanted, potentially causing adverse clinical reactions such as coagulation and thrombosis, impairing the performance of implanted energy storage devices, and posing a serious threat to human health. Therefore, this work aims to design an anticoagulant supercapacitor by heparin doped poly(3, 4-ethylenedioxythiophene) (PEDOT) for possible applications in implantable bioelectronics. Heparin (Hep), the as-known anticoagulant macromolecule acts as the counterion for PEDOT doping to enhance its conductivity, and the bioelectrode material PEDOT: Hep with anticoagulant activity is synthesized via chemical oxidation polymerization. Concurrently, the anticoagulant supercapacitor is constructed through in-situ polymerization, where PEDOT: Hep and bacterial cellulose as electrode material and electrolyte layer, respectively. Owing to the incorporation of heparin, the supercapacitor exhibits high hemocompatibility with hemolysis rate

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
15
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.40662c1c60442299ac7168224f38547
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-024-54862-2