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Lymphadenectomy in Primary Fallopian Tube Cancer is Associated with Improved Survival
- Source :
- Journal of Investigative Surgery, Vol 35, Iss 6, Pp 1417-1423 (2022)
- Publication Year :
- 2022
- Publisher :
- Taylor & Francis Group, 2022.
-
Abstract
- Background and Objectives Primary fallopian tube cancer (PFTC) shares the same diagnostic and management guidelines with epithelial ovarian cancer (EOC). The LION trail raised concerns regarding the role of systematic pelvic and para-aortic lymphadenectomy during debulking surgery. We aimed to evaluate the significance of lymphadenectomy in PFTC survival. Methods This retrospective study analyzed the clinical features and survival of patients with PFTC who underwent primary surgery in our center between January 2013 and October 2020. Results Sixty-one patients diagnosed with PFTC were included in the study. Twenty-five (41.0%, 25/61) were diagnosed with FIGO (International Federation of Gynecology and Obstetrics) stages I/II and 36 (59.0%, 36/61) were diagnosed with stage III/IV. Twenty-nine (47.5%, 29/61) underwent pelvic lymphadenectomy with or without para-aortic lymphadenectomy, among which 12 (41.4%, 12/29) had lymph node metastasis confirmed by postoperative pathology. The mean progression-free survival was 60.4 months in the lymphadenectomy group and 37.8 months in the no-lymphadenectomy group (p = 0.042, HR 0.374, 95% CI 0.145–0.966). Conclusions PFTC is often diagnosed earlier and has a better prognosis than EOC. Most patients with PFTC would benefit from lymphadenectomy. However, the extent to which this association translates to a more diverse population needs to be further identified.
- Subjects :
- gynecology
lymphadenectomy
fallopian tube cancer
surgery
prognosis
Surgery
RD1-811
Subjects
Details
- Language :
- English
- ISSN :
- 08941939 and 15210553
- Volume :
- 35
- Issue :
- 6
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Investigative Surgery
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.40eb97436fac47c199c8a98ea982ead6
- Document Type :
- article
- Full Text :
- https://doi.org/10.1080/08941939.2022.2048142