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Neutrophil percentage-to-albumin ratio predicts mortality in bladder cancer patients treated with neoadjuvant chemotherapy followed by radical cystectomy

Authors :
Matteo Ferro
Dragoş-Florin Babă
Ottavio de Cobelli
Gennaro Musi
Giuseppe Lucarelli
Daniela Terracciano
Angelo Porreca
Gian Maria Busetto
Francesco Del Giudice
Francesco Soria
Paolo Gontero
Francesco Cantiello
Rocco Damiano
Papalia Rocco
Roberto Mario Scarpa
Abdal Rahman Abu Farhan
Riccardo Autorino
Antonio Brescia
Michele Marchioni
Andrea Mari
Andrea Minervini
Nicola Longo
Francesco Chiancone
Sisto Perdona’
Biagio Barone
Pietro De Placido
Michele Catellani
Danilo Bottero
Pasquale Ditonno
Michele Battaglia
Stefania Zamboni
Alessandro Antonelli
Francesco Greco
Giorgio Ivan Russo
Salvatore Smelzo
Rodolfo Hurle
Nicolae Crisan
Matteo Manfredi
Francesco Porpiglia
Felice Crocetto
Carlo Buonerba
Alina Danilesco
Mihai Dorin Vartolomei
Source :
Future Science OA, Vol 7, Iss 7 (2021)
Publication Year :
2021
Publisher :
Taylor & Francis Group, 2021.

Abstract

Aim: To investigate the prognostic role of neutrophil percentage-to-albumin ratio (NPAR) in muscle-invasive bladder cancer (MIBC) patients treated with neoadjuvant chemotherapy (NAC) and radical cystectomy (RC). Patients & methods: 213 patients were included. Inclusion criteria: Nonmetastatic, MIBC (cT2-T4aN0M0), at least three cycles of NAC, undergone RC and with blood count within 30 days before NAC. Results: Five-years overall survival (OS) with NPAR >18 was 34.06% (95% CI: 18.3–50.5) and 65.37% (95% CI: 52.4–75.6) with NPAR 18 was 42.9% (95% CI: 23.9–60.7) and 74.5% (95% CI: 62.6–83.1) with NPAR

Details

Language :
English
ISSN :
20565623
Volume :
7
Issue :
7
Database :
Directory of Open Access Journals
Journal :
Future Science OA
Publication Type :
Academic Journal
Accession number :
edsdoj.4222e22b8a814a31a4ac338851ea9349
Document Type :
article
Full Text :
https://doi.org/10.2144/fsoa-2021-0008