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Muscle mass and estimates of renal function: a longitudinal cohort study
- Source :
- Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2031-2043 (2022)
- Publication Year :
- 2022
- Publisher :
- Wiley, 2022.
-
Abstract
- Abstract Background Creatinine is the most widely used test to estimate the glomerular filtration rate (GFR), but muscle mass as key determinant of creatinine next to renal function may confound such estimates. We explored effects of 24‐h height‐indexed creatinine excretion rate (CER index) on GFR estimated with creatinine (eGFRCr), muscle mass‐independent cystatin C (eGFRCys), and the combination of creatinine and cystatin C (eGFRCr‐Cys) and predicted probabilities of discordant classification given age, sex, and CER index. Methods We included 8076 adults enrolled in the PREVEND study. Discordant classification was defined as not having eGFRCr
Details
- Language :
- English
- ISSN :
- 21906009 and 21905991
- Volume :
- 13
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Cachexia, Sarcopenia and Muscle
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.42d1205f8b1487b97d426f71b14d20a
- Document Type :
- article
- Full Text :
- https://doi.org/10.1002/jcsm.12969