Back to Search
Start Over
Extranodal lymphoma in a bush dog (Speothos venaticus) - case report
- Source :
- Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol 72, Iss 3, Pp 754-760 (2020)
- Publication Year :
- 2020
- Publisher :
- Universidade Federal de Minas Gerais, 2020.
-
Abstract
- ABSTRACT A captive 7-year-old male bush dog (Speothos venaticus) was diagnosed with lymphoma affecting the kidneys, adrenal glands, liver, and spleen. The animal developed renal failure and was euthanized due to poor prognosis. Grossly, both kidneys were enlarged with multiple nodules. Histologically, the neoplasm was an infiltrative and poorly demarcated round cell tumor. Two morphologically distinct cell populations were observed, smaller cells with a lymphocytic morphology, and another population of larger and pleomorphic cells. Most of the smaller cell population, approximately 40% of the population within the neoplasm, were CD3 positive. Neoplastic cells were CD45, CD11d, and granzime B positive, and negative for CD20, CD79a, PAX5, CD163, and myeloperoxidase. This is the first reported case of lymphoma in a bush dog. This report demonstrated the suitability of several cell surface markers for differential diagnosis of round cell tumors in this species.
- Subjects :
- lymphoma
immunohistochemistry
neoplasm
wildlife
Animal culture
SF1-1100
Subjects
Details
- Language :
- English, Portuguese
- ISSN :
- 16784162
- Volume :
- 72
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Arquivo Brasileiro de Medicina Veterinária e Zootecnia
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.43b8928640ac474c916d1d698aecfad3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/1678-4162-11435