Back to Search Start Over

The transferability of lipid loci across African, Asian and European cohorts

Authors :
Karoline Kuchenbaecker
Nikita Telkar
Theresa Reiker
Robin G. Walters
Kuang Lin
Anders Eriksson
Deepti Gurdasani
Arthur Gilly
Lorraine Southam
Emmanouil Tsafantakis
Maria Karaleftheri
Janet Seeley
Anatoli Kamali
Gershim Asiki
Iona Y. Millwood
Michael Holmes
Huaidong Du
Yu Guo
Meena Kumari
George Dedoussis
Liming Li
Zhengming Chen
Manjinder S. Sandhu
Eleftheria Zeggini
Understanding Society Scientific Group
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

The majority of published GWAS was performed in European ancestry populations. Here, Kuchenbaecker et al., test to which extent lipid loci are shared and find that the major lipid loci are mostly transferrable between Europeans and Asians while there are notable exceptions for African populations.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.442fbc04a95d4e22903a961fed36fb1d
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-12026-7