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Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- The mesothelium supports homeostasis and regeneration, yet its development origins remain unclear. Here, the authors uncovered the earliest mesothelium progenitor cells in zebrafish, linking Hand2 gene function to mesothelium formation and its re-activation to mesothelioma tumors.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.445f40166b9345a1905f77ae35cd17f3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-29311-7