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Epigenetic aging of the demographically non-aging naked mole-rat

Authors :
Csaba Kerepesi
Margarita V. Meer
Julia Ablaeva
Vince G. Amoroso
Sang-Goo Lee
Bohan Zhang
Maxim V. Gerashchenko
Alexandre Trapp
Sun Hee Yim
Ake T. Lu
Morgan E. Levine
Andrei Seluanov
Steve Horvath
Thomas J. Park
Vera Gorbunova
Vadim N. Gladyshev
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The exceptionally long-lived naked mole-rat is characterized by the lack of increased mortality with aging. Here the authors perform epigenetic studies to show that naked mole-rats epigenetically age despite their non-increasing mortality rate.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.44f348039b714784b3968f7be0bc9284
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-27959-9