Back to Search Start Over

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne

Authors :
Christos Petridis
Alexander A. Navarini
Nick Dand
Jake Saklatvala
David Baudry
Michael Duckworth
Michael H. Allen
Charles J. Curtis
Sang Hyuck Lee
A. David Burden
Alison Layton
Veronique Bataille
Andrew E. Pink
The Acne Genetic Study Group
Isabelle Carlavan
Johannes J. Voegel
Timothy D. Spector
Richard C. Trembath
John A. McGrath
Catherine H. Smith
Jonathan N. Barker
Michael A. Simpson
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Acne vulgaris is a chronic inflammation of the skin, the genetic basis of which is incompletely understood. Here, Petridis et al. perform GWAS and meta-analysis for acne in 26,722 individuals and identify 12 novel risk loci that implicate structure and maintenance of the skin in severe acne risk.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.452ea8192e3a4a489db21942afed2d37
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-07459-5