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Impact of the gut microbiota on the m6A epitranscriptome of mouse cecum and liver

Authors :
Sabrina Jabs
Anne Biton
Christophe Bécavin
Marie-Anne Nahori
Amine Ghozlane
Alessandro Pagliuso
Giulia Spanò
Vincent Guérineau
David Touboul
Quentin Giai Gianetto
Thibault Chaze
Mariette Matondo
Marie-Agnès Dillies
Pascale Cossart
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

The intestinal microbiota modulates host physiology and gene expression via unclear mechanisms. Here, Jabs et al. show that variations in the gut microbiota correlate with N6-methyladenosine modifications of host mRNAs in the cecum and liver of mice.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.4616a2618284d1b9a065bb464d89fe3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-15126-x