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Pathophysiological pathway differences in children who present with COVID-19 ARDS compared to COVID -19 induced MIS-C

Authors :
Conor McCafferty
Tengyi Cai
Delphine Borgel
Dominique Lasne
Sylvain Renolleau
Meryl Vedrenne-Cloquet
Damien Bonnet
Jemma Wu
Thiri Zaw
Atul Bhatnagar
Xiaomin Song
Suelyn Van Den Helm
Natasha Letunica
Chantal Attard
Vasiliki Karlaftis
Slavica Praporski
Vera Ignjatovic
Paul Monagle
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

While rare, SARS-CoV-2-infected children can develop severe COVID-19 (ARDS) or inflammatory syndrome (MIS-C). Here, the authors use proteomics to characterize hundreds of blood proteins and identify key biological pathways that differentiate MIS-C and ARDS.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.466b607d69b2424ab603489b29f3f57d
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-29951-9