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Survival in elderly patients with breast cancer with and without autoimmune disease

Authors :
Demitrios Dedousis
Annie L. Zhang
Anastasia N. Vassiliou
Shufen Cao
Deepthi Yammani
Ravi K. Kyasaram
John P. Shanahan
Melissa C. Keinath
Melinda L. Hsu
Pingfu Fu
Afshin Dowlati
Alberto J. Montero
Source :
Cancer Medicine, Vol 12, Iss 12, Pp 13086-13099 (2023)
Publication Year :
2023
Publisher :
Wiley, 2023.

Abstract

Abstract Background Patients with certain autoimmune conditions are at a reduced risk of developing breast cancer compared to the general population. Despite this, little is known about outcomes in patients with breast cancer who have a concurrent autoimmune diagnosis. Methods This study compared differences in outcomes between women with breast cancer who had or did not have an autoimmune diagnosis. The SEER‐Medicare databases (2007–2014) were used to identify patients with breast cancer and diagnosis codes were used to identify those with an autoimmune disorder. Results The studied autoimmune diseases had a prevalence of 27% among the 137,324 patients with breast cancer. Autoimmune disease was associated with significantly longer overall survival (OS) and significantly lower cancer‐specific mortality (CSM) among stage IV breast cancer patients (p

Details

Language :
English
ISSN :
20457634
Volume :
12
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Cancer Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.48f597776f8d4666879c67d21dc5d57b
Document Type :
article
Full Text :
https://doi.org/10.1002/cam4.5989