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A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response

Authors :
Yi-Chun Lin
Chien-Yu Cheng
Cheng-Pin Chen
Shu-Hsing Cheng
Sui-Yuan Chang
Po-Ren Hsueh
Source :
International Journal of Infectious Diseases, Vol 96, Iss , Pp 464-466 (2020)
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

We report the case of a patient who had travelled to Japan and who presented mild respiratory symptoms during the COVID-19 outbreak period. There was transient existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in his oropharynx. The RNA was absent in the six respiratory specimens that were subsequently tested. An anti-SARS-CoV-2 antibody response was absent in the acute and convalescent sera. The reported case indicates that transient colonization of SARS-CoV-2 in the upper respiratory tract is possible without inciting any antibody response against the virus.

Details

Language :
English
ISSN :
12019712
Volume :
96
Issue :
464-466
Database :
Directory of Open Access Journals
Journal :
International Journal of Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.491376f92899445cad793f636af9c18f
Document Type :
article
Full Text :
https://doi.org/10.1016/j.ijid.2020.05.070